There are a number of paid software that allow you to optimize your PC performing many important tasks.

Glary Utilities is a program that offers all these tools to speed up and optimize your computer. Optimization modules include registry cleaning, disk cleaning, shortcut fixing, uninstall manager, startup manager, memory optimizer, file shredder, duplicate files finder, etc.

Features

• Optimize, clean and boost the speed of your Windows.
• Protect your privacy and security.
• Block spyware, trojans, adware, etc.
• Fix certain application errors.
• Simple, fast and User friendly interface

Download here

I still use CCleaner for deleting unwanted files and repairing the registry but this program has many advanced features not available in free programs.